Kosmetische Medizin 6-2009: 222 – 224

Subluminescence-PDT shows good outcomes in the treatment of carcinomas, precanceroses and viral warts

WOLFGANG STRASSER (FREIBURG), DAGMAR ROHDE (KIEL), JÖRG ZIMMERMANN (GERLINGEN)

KEY WORDS: Basal cell carcinoma, actinic keratosis, photodynamic therapy, subluminescence-PDT, viral warts

SUMMARY:
Photodynamic therapy (PDT) has found wide deployment in Dermatology. Especially the application in the treatment of skin cancer (i.e. basal cell carcinoma) and their pre-stages, i.e. actinic keratosis. Promising experiences, studies and single reports also suggest good results in the treatment of viral warts and other hyperceratotic skin lesions.

One disadvantage of PDT is the low depth of penetration. The newer subluminescence-PDT, however, permits a targeted application for local circumscribed skin lesions that demand a deeper penetration of light. Because of the promising results, SL-PDT in the treatment of local, circumscribed hyperceratotic tumorous lesions and plantar warts is documented in a multicenter open pilot study in daily practice.