Kosmetische Medizin 2-2011: 66-69

POROKERATOSIS – A COMPARATIVE 10-YEAR ANALYSIS FROM GUJARAT AND SAXONY
WITH PRESENTATION OF A NEW CASE OF PTYCHOTROPIC POROKERATOSIS

UWE WOLLINA1, SHYAM B. VERMA2, MICHAELA TILP1, JAQUELINE SCHÖNLEBE3, GUNTER HAROSKE3

1 Academic Teaching Hospital Dresden-Friedrichstadt, Department of Dermatology and Venerology,
Friedrichstrasse 41, 01067 Dresden, Germany; wollina-uw@khdf.de.
2 Nirvana Skin Clinic, B3 C.S. Patel Enclave, 3 Pratapguij, Vadodara 3900002, India; skindiaverma@googlemail.com.
3 Academic Teaching Hospital Dresden-Friedrichstadt, Institute of Pathology “Georg Schmorl”,
Friedrichstrasse 41, 01067 Dresden, Germany; haroske-gu@khdf.de.

KEY WORDS: Disorders of keratinisation, porokeratosis, Fitzpatrick skin phototype, UV-exposure

SUMMARY:
Background: Porokeratosis covers a spectrum of disorders of keratinization with variable clinical presentation and non-uniform genetic background. Some types are highly associated with UV-exposure. We analyzed a 10-year period for occurrence of porokeratosis in two geographically different settings, one with high UV-exposure and one with medium to low UV-exposure.

Patients and methods: Clinico-pathologic files of the Nirvana Skin Clinic in Vadodara, Gujarat/India, and the Department of Dermatology & Allergology of the Academic Teaching Hospital Dresden-Friedrichstadt, Dresden/Germany were analyzed for porokeratosis between January 2000 and August 2010. The predominant skin phototypes were either Fitzpatrick type III or higher (India) or I and II (Germany).

Results: In Vadodara, two cases of ptychotropic porokeratosis in children were identified. In Dresden all cases of porokeratosis were seen in adults only with superficial actinic porokeratosis as the predominant type. Skin phototype, genetic background, and UV-exposure seem to be major factors influencing the clinical presentation of porokeratosis. Limitations: No population-based data on prevalence and no genetic data were available.

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